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Genetic Entropy & the Mystery of the Genome Paperback – 1 Mar 2008


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Genetic Entropy & the Mystery of the Genome + IN THE BEGINNING WAS INFORMATION PB + Signature in the Cell: DNA and the Evidence for Intelligent Design
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Product details

  • Paperback: 248 pages
  • Publisher: Feed My Sheep Foundation, Inc. (1 Mar 2008)
  • Language: English
  • ISBN-10: 0981631606
  • ISBN-13: 978-0981631608
  • Product Dimensions: 15.6 x 1.5 x 23.4 cm
  • Average Customer Review: 4.7 out of 5 stars  See all reviews (9 customer reviews)
  • Amazon Bestsellers Rank: 266,665 in Books (See Top 100 in Books)

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Customer Reviews

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Most Helpful Customer Reviews

10 of 11 people found the following review helpful By R. J. Allen on 25 April 2010
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I found this book revolutionary - I was aware of the general principle that mutations in the genome are more likely to push evolution backwards - but this book confirms what the evidence shows, that all living things are slowly dying - mutational overload is slowly making everything less able to survive, thus extinctions have been the order of the day throughout many generations. John Sandford draws on a lifetime of experience in genetics to expose the fraud of evolutionary dogma for what it is. This should be required reading for all those who are busy advancing the theory of evolution as the the ultimate explanation for all things!
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1 of 1 people found the following review helpful By Lloyd To on 27 Sep 2014
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Evolution or Devolution?

This is a very informative and cogently argued book, supported by ample documentation. There is much discussion of population genetics. However, the author's concern is not with the mathematical models but rather the assumptions underpinning them. As an accomplished experimental geneticist, John Sanford is well qualified to evaluate these assumptions.

The text is semi-technical, and readers with no background in genetics will find it heavy going, especially as some of the technical terms are omitted from the glossary.

The book's main thrust is the net long term degradation of the genome. The author likens random errors in DNA replication to typing errors in copying a document. Such random changes do not produce a more highly organised text, i.e. one that conveys the information more effectively or even adds additional meaningful information. Likewise, mutations due to copying error and environmental damage (radiation or toxins) degrade the DNA text.

Moreover, most DNA sequences are poly-functional. For example, most human coding sequences encode for two different RNAs that read in opposite directions. Some sequences encode for different proteins, depending on where translation is initiated. Some encode for different proteins based on alternate splicing. This poly-functional nature of DNA powerfully reinforces the above argument that random changes will result in degradation of the code.

The threat posed by mutations had been recognised long before "Genetic Entropy" was published. Tens of thousands of diseases caused by mutations have been catalogued, while it is hard to find any uncompromisingly beneficial mutations.
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2 of 2 people found the following review helpful By Booksmith on 3 Aug 2013
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This is an exceptional work. Fairly easy to follow for most people, although it can get a little technical at times. Anyone with a college level (or higher) standard of education will be able to follow without much difficulty. A very worthwhile contribution to the origins debate, written by a scientist with first class credentials.
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1 of 1 people found the following review helpful By HermanB on 14 Jan 2013
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This is a very actual book on the issue of evolution. The author gives tough scientific arguments that life on earth cannot be there by incidence. Very actual questions are discussed in a balanced and professional way. I am impressed! A very helpful book for those who have not yet made up their mind on the question: How did the human genome develop?
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By K. B. Betts on 23 Jun 2014
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Excellent! Like the author I have never understood the slavish acceptance of the theory of evolution when any real investigation reveals just how incongruous it is. How often people miss that it is merely someone's theory
Serious investigation quickly reveals the idea of mutation leading to overall improvement of the genome as fallacy.
The stubborn clinging to theory dressed as fact requires a level of blind faith far beyond that which adherents repeatedly accuse Christian believers of holding. Careers have been built on these absurdities and they have become fiercely defended as an orthodoxy has been put in place around them. Many seem to think that this orthodoxy is unassailable. Not so.
I challenge anyone with a serious interest to buy and read this. It should be a best seller and on everyone's reading list.
C.B.
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