I'll be joining a fixed income trading desk in a few months and picked up this book to gain some additional insights. If you have some exposure to the fixed income markets, this book will do a wonderful job of supplementing that knowledge. The chapters on pricing the roll, determining richness/cheapness to the curve, and financing (i.e., repo) are invaluable. As another reader mentioned, the writing is a bit outdated, but it still provides a lot of good information. I think it also focuses too much on Macaulay duration at the outset, leaving aside the more often-used DV01 (Garbade refers to it as "value of a basis point") until much later. Still, there are few good books on the subject of fixed income markets, and this is definitely one of them.