In recent decades the number of diagnostic equipments has been increasing at an exponential rate. Ophthalmology in particular has seen explosion of diagnostic devices. However, compared to the advances in clinical research, the methodology of diagnostic research is lagging. There are no broadly accepted formal requirements for validity and effectiveness that diagnostic tests must comply before being incorporated in daily clinical practise.
This book accumulates the recent and best available evidence from the forefront in diagnostic research. The second edition includes two extra chapters (chapter 8 and 9) and a completely re-written chapter 11. The extra chapters include a chapter on multi-variable analysis in diagnostic research and a chapter on Standards for Reporting Diagnostic accuracy studies (STARD). The STARD guidelines have become an essential checklist for submitting manuscript in most leading scientific journals. The chapters are written by leaders in the field with up-to-date references. The book is written in a simple language to explain what is thought to be a complex topic.
An invaluable reference for ophthalmologists involved in conducting or interpreting studies on diagnostic research.