This is a huge book that actually lives up to its size. It's not one of those design books that kind of looks nice and then ends up on your shelf, it's actually full of great anecdotes, experiences and lessons from people who've made great (and not so great) stuff. Oh and it has a DVD of videos from those same people too. Fantastic.
If you design anything remotely interactive, from a website to a bottle-opener, you should own this.