This book constitutes an incredibly good review of the history of neuroscience from Descartes, Pavlov and early theories of the brain and reflexes to more modern interpretations of the brain, neurons, neural networks, etc. It introduces the idea of neuroeconomics in a manner suitable to the layperson. If that is what Glimcher was setting out to do, then this book has achieved exactly that.
However, I believe that as a discussion of 'decisions and uncertainty' the book could have used more formalism in expressing some of its arguments, specifically in possible theories of how and why things work in the way proposed by the author. Admittedly, I could be asking too much of the field at this point as it is still in its early stages of development, but occasionally I wanted more than anecdotes and discussions of papers that the author and his co-workers had written. Again, maybe I am expecting too much, but I had thought that Neuroeconomics had accomplished more.
Thus, in my 'layperson' hat, I think the book was great. It revealed a lot of theory that I would not likely have read otherwise, though being interested in and having read of specific individuals previously.
However, in my 'economist grad student' hat, I wanted something more. It definitely warrants more research. Moreover, the fact that the book supports inter-disciplinary research and the rigour of it generally far outweighs these slight shortcomings.