The world is now populated, largely, by vampires, a situation arising from the spread of a plague initiated by a single individual human being bitten by a vampire bat. The vampires, on the face of it, want to live cooperatively with humans but with a desperate need for blood what's a health-conscious vamp to do? One solution is to make synthetic blood. This is the solution that the giant corporation, Bromley Marks has invested in with top vampire haematologist, Edward Dalton (Ethan Hawke), leading the research team. However, the progress the team are making in the development of the synthetic product is not fast enough to meet the increasing demand from the vampire public. The result is that humans are rounded up for `farming' in a 'Matrix style' industrial scale extraction complex while the research continues.
Naturally enough the few remaining humans take exception to this and form a resistance group led by `Elvis' Cormac, played by the always watchable, Willem Defoe, a former vampire, who was `cured' by being, one day, accidentally exposed to the full glare of the Sun and then suddenly `quenched' by driving into a handy lake! Driving home from work one day Dalton encounters a group of humans whose car has broken down and he offers them refuge from the hunter vampires in his car. As a result he meets Cormac who relates the incident that cured him. From that moment on Dalton, already sympathetic to the humans' plight throws in his lot with them.
The film looks good on blu ray, has a few gory moments when blood-starved vamps go on a feeding frenzy, conveys a key economic principle of supply and demand, and, interestingly, makes an unwitting if timely point about the bloodsucking nature of big business in the form of evil tycoon Charles Bromley, ably portrayed by Sam Neill. The disc also has, as an extra feature, a brilliant 15 minute short film called The Big Picture, which is almost worth the price of the disc alone!