1 of 1 people found the following review helpful:
3.0 out of 5 stars
Disingenuous, but thought-provoking, 11 Oct 2011
Gosh, what a funny old book. Subtitled 'The Biochemical Challenge to Evolution', Behe's work starts as an intelligent dig at some apparent holes in the Darwinist literature and ends as a not-quite-overt Creationist tract.
Behe is a biochemist, and also, as we learn 15 pages from the book's close, a Roman Catholic. His argument is a compelling one: that Darwinists focus almost exclusively on gross anatomy, yet the kinds of changes they invoke on the road to, say, the human eye, are never elucidated at the detailed molecular level. This, says Behe, is a gigantic con trick since the smallest phenotypic effect can require intricate and massive changes at the level of biochemistry and hence would not be attainable by natural selection.
It's a good idea, and somewhat convincing in the context of Behe's examples. His argument centres on 'irreducible complexity', which suggests that there are systems in biology that simply could not have evolved gradually, and he eventually (on page 193) comes clean and states that the systems he's described (cilia, blood clotting, etc.) were 'clearly' designed by an intelligent being.
The examples Behe considers are deliberately complex, yet his assertion that such systems are irreducibly complex is undermined by his own attack on the 'argument from personal incredulity' - just because he considers such system irreducible doesn't necessarily mean that they are so. His mousetrap example is particularly unconvincing, although we shouldn't let this obscure his basic point, which is that if natural selection can't explain an irreducibly complex system, we must, on Darwin's own admission, discard it as a natural philosophy.
Behe certainly has some interesting things to say about questioning our beliefs and why we hold such beliefs in the first place, but ultimately his message will stand or fall on details that we laymen must take on trust. His suggestion that science must explain the actual detailed route by which any evolutionary step took place seems ill-founded, and it all goes a bit pear-shaped towards the end, when he reveals his Creationist agenda.
For all that, it's a thought-provoking read.
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19 of 24 people found the following review helpful:
3.0 out of 5 stars
Open the box, 7 Jan 2008
The basic argument is that evolution by a gradual series of random mutations cannot account for the development of highly complex ,resolved and irreducible bio-chemical networks.
It does not do justice to this book to portray this debate as religion v science.
The fact is that we struggle to explain the evolution of life on Earth from pre-biotic chemicals;or the evolution of DNA and its sophisticated interaction with proteins.
It is no bad thing to remain sceptical of whether nineteenth and early twentieth century scientific theory is really adequate to fully explain the outstanding complexity or the brilliantly conceived and engineered solutions of nature.
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35 of 50 people found the following review helpful:
4.0 out of 5 stars
A biochemist responds to Behe's challenge, 23 Mar 1999
By A Customer
As a biochemist interested in DNA structures and the origins of complex systems, I was delighted to hear that someone in my area of research had written a book on this subject. Behe does a good job of trying to convey the problem. If anything, molecular systems are even MORE complex than detailed in his well written and wonder-filled descriptions. However, I was surprised and frustrated to find the use of poor logic and factual errors throughout the book. For example, Behe can't find articles that he LIKES about the molecular evolution of flagella, so he then proceeds to claim that these articles simply don't exist. There are entire textbooks with titles like "Molecular Evolution" (search Amazon.com and see for yourself), and yet Behe insists that nothing has been written on the subject, and concludes that the reason for this is because no one has been able to find any detailed evidence for molecular evolution.
One of the examples cited of "irreducible complexity" is the bacterial flagellum. Behe claims that 40 proteins are necessary for a fully functional flagellum. Whilst this is true for E.coli, flagella in many bacteria are made from fewer proteins - for example, in the bacterium that causes syphilis (Treponema pallidum), there are a total of 38 flagellar proteins; in the bacterium that causes lyme disease (Borrelia burgdorferi), there are only 35 flagellar proteins; finally, in a bacteria associated with ulcers (Helicobacter pylori) there are only 33 proteins necessary to form complete, fully functional flagella. It is likely that as new bacterial genomes continue to be sequenced (at the rate of about one a month!), organisms will be found which require even fewer genes to make a completely functional flagella. So this "irreducible complex" of 40 proteins has shrunk to 33 proteins, in the past 2 years of research! Behe's argument is that EVERY ONE of the 40 proteins are necessary. Obviously 7 of those 40 aren't completely necessary. Maybe it's only 30 or perhaps even 20 proteins that are absolutely necessary? It's hard to say, but it is very dangerous to make such dogmatic statements as "this system is irreducibly complex", especially when the system is made up of proteins that have other normal functions in the cell, apart from flagella - such as the GTPase proteins. For a more fair treatment of the subject of flagella (and bacteria and molecular evolution in general), I can happily recommend reading "The Outer Reaches of Life", by John Postgate (also available through Amazon.com), which is an excellent treatise about bacteria written for the "non-scientific reader".
Of course there is a need to explain the origins of biochemical complexity. But declaring "intelligent design by a miracle" to be this method is neither scientific nor helpful. I guess my advice would be similar to that of Huxley about Darwin's Origin of the Species - please read Behe's book and decide for yourself!
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