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Dark Remedy: The Impact of Thalidomide and Its Revival as a Vital Medicine [Paperback]

Stephens
3.7 out of 5 stars  See all reviews (3 customer reviews)
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Book Description

6 Dec 2001
"A thoughtful account of the rise, fall, and subsequent rise again of thalidomide's fortunes."-Richard Horton, editor of The Lancet, in The New York Review of Books. In this riveting medical detective story, Trent Stephens and Rock Brynner recount the history of thalidomide, from the epidemic of birth defects in the 1960's to the present day, as scientists work to create and test an alternative drug that captures thalidomide's curative properties without its cruel side effects. A parable about compassion-and the absence of it-Dark Remedy is a gripping account of thalidomide's extraordinary impact on the lives of individuals and nations over half a century.

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Product details

  • Paperback: 240 pages
  • Publisher: Basic Books (6 Dec 2001)
  • Language: English
  • ISBN-10: 0738205907
  • ISBN-13: 978-0738205908
  • Product Dimensions: 14 x 1.6 x 21 cm
  • Average Customer Review: 3.7 out of 5 stars  See all reviews (3 customer reviews)
  • Amazon Bestsellers Rank: 716,637 in Books (See Top 100 in Books)

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About the Author

Rock Brynner, historian and novelist, earned his M.A. in Philosophy from Trinity College, Dublin, and his Ph.D. in History from Columbia University. This is his fifth book. Trent Stephens, Professor of Anatomy and Embryology at Idaho State University, is the author of numerous books. He has been researching thalidomide for almost twenty-five years.

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THE BIRTH OF UTOPIA IN THE 1950S proclaimed an era of new dreams. Read the first page
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Customer Reviews

3.7 out of 5 stars
3.7 out of 5 stars
Most Helpful Customer Reviews
6 of 6 people found the following review helpful
4.0 out of 5 stars A reminder of folly and hope for the future 16 Jun 2001
By A Customer
Format:Hardcover|Amazon Verified Purchase
The book consists of two parts.

The first is the history of the thalidomide disaster which resulted in the mutilation of many unborn children exposed to the drug taken by their mothers in a short period of their early pregancy. This includes information on the amazing activities of the companies who developed and marketed the products containing the drug, and on the legal systems (one can hardly talk about 'justice', especially in the UK, until the matter was taken up in the European human rights court).

The second part of the book is concerned with the more recently identified uses for the drug in rare diseases involving the immune system, including some AIDS-related conditions, and a range of autoimmune sydromes. This part also includes some information on recent discoveries relating to the way in which thalidomide caused the deformation in fetuses.

Not a book for the squeamish, but an important reminder - particularly on the ethics of the pharmaceutical industry in the 1950s and 60s.

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1 of 1 people found the following review helpful
5.0 out of 5 stars The story behind thalidomide 23 Sep 2011
Format:Paperback
This is well-written book about thalidomide - it's history, side effects and present day therapeutic uses, although more powerful and safer derivatives are now available for the treatment of cancer and leprosy. The fact that a single tablet can have such devasting effects on the human fetus was one of the factors leading to the acceptance of abortion in the US.
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1 of 1 people found the following review helpful
2.0 out of 5 stars Could be better 27 Dec 2007
Format:Paperback
Until I reached chapter 5 on the effect of Thalidomide in Great Britain I was impressed by how well written and readable this book was and took what it said at face value.

It is difficult to judge a book about something of which one has very little knowledge but when it touches on a subject one does know something about one can begin to make such a judgement.

It says of the highest court in Great Britain

"Since there is no separation of powers , instead of an independent Supreme Court there is a court of Parliament: a tribunal of the aristocracy within the House of Lords decides the fate of such cases that float to the top, unresolved in lower courts"

This is so misleading as to be completely wrong. The House of Lords is our supreme court but it is not made up of members of the aristocracy with nothing better to do. The Judges in the House of Lords are appointed from the cream of the Judiciary, who themselves are selected from the cream of our barristers. If a judge is chosen to sit in the House of Lords he will be granted a peerage if he has not already been given one for services to the Law.

The Judges are made peers, the peers are not made judges. As in United States once appointed they cannot be dismissed.

The statement in the book indicates a total lack of a research on this matter and given the fact that Rock Brynner's original degree was from Trinity College Dublin the error is unforgivable.

In the very next paragraph the book makes the following statement.

"The Tories choice to lead the National Health Service is incongruous enough to guarantee a chuckle of disbelief, to those familiar with his name: Enoch Powell, the Minister for health during the thalidomide crisis, was the fanatical Conservative who became England's most outspoken and unapologetic racist railing against immigrants, Indian and Pakistanis in particular".

It is clear that all he is familiar with is the name. Once again it is clear that no serious research has been done and they know nothing about the man and his history.

Enoch Powell studied classics and became the youngest professor in the British Empire when he became Professor of Greek at the University of Sydney at the age of 25. When War broke out in 1939 he left Australia and enlisted in the British Army as a Private. He left the Army at the end of the war as the youngest Brigadier in the British Army (roughly the equivalent of a One Star General in the US Army).

Whether he ever was a racist is a serious question for Historians. It is true he made a speech pointing out that uncontrolled immigration would cause racial tensions which would be likely to lead to violence. (this proved correct). However:

1. He was one of only two MPs who forced Parliament to do something about the treatment of Mau Mau Terrorists detained by the British in Kenya.

2. As Minister of Health he oversaw a huge increase in the number of coloured people employed in the NHS.

3. There is no evidence that he treated his black and Asian constituents any differently from his white constituents.

4. One of the languages he spoke was Hindi.

He was certainly a maverick who said what he thought however unpopular that might have been. He was not a particularly pleasant person. Although he was certainly branded a racist, the evidence to support that accusation is at best ambiguous. What is certain is that intellectually he was something of a giant.

Once again the quality of the historical research was positively shoddy and there is a certain element of vindictiveness about some of comments in the book. One fears that expressing this vindictiveness might have overtaken any desire to present the truth.

Overall I am left with the feeling that no one can really rely on any of the statements made about the history of Thalidomide.

This is sad. Those who suffered deserve better.
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