Poor Dr. Thomas Bolton (Karloff). He's a compassionate, elderly British surgeon in the days before anesthesia. Tired of seeing his patients undergo excruciating agonies on the operating table, Bolton is working doggedly to concoct a drug which will banish pain and allow his patients to feel nothing during surgery. A failed and humiliating demonstration of his new drug before his professional peers makes Bolton even more determined to prove them wrong when they insist, "Pain and the knife are one."
Alas, as Bolton conducts experiments upon himself in pursuit of his dream, he becomes addicted to his own formula. His hands - once known for their speed with a knife in the surgical theatre - shake and betray him. His memory fails him; he can't remember what happens to him while under the sway of his formula. He begins to deteriorate.
The hospital's executive committee denies Bolton another chance to prove his work's validity and puts him, more or less, on "informal leave", suspending his privileges at the hospital's dispensary - the only place he can get the drugs necessary for both his research and his addiction.
Bolton falls in with a reprehensible crowd of no-gooders, including the elegant but menacing Resurrection Joe (Christopher Lee), a soulless killer with a penchant for smothering his victims with pillows. In return for getting Dr. Bolton the drugs he now craves both for his experiments and for himself, these body snatchers, who have been murdering drunken alehouse customers and passing them off as natural deaths, manipulate Bolton into a Faustian bargain to sign the death certificates of their hapless victims so they might sell the bodies to the hospitals for teaching purposes and collect the money.
The reason I gave this DVD only 4 stars, rather than 5, had nothing whatsoever to do with my total enjoyment of this film. Indeed, the print is excellent and the sound quality clear and distinctive. The one complaint I have is that there is only one "extra" on the DVD - the film's original theatrical trailer. I would have liked to have seen at least an interactive cast listing and additional information on the film itself.
Other than that, it's great to see Karloff and Lee in the same production. They just ... belong together in a movie frame, I think. The violence is more implied than shown, making poor Bolton's situation even more tragic, and Karloff plays him sympathetically yet strongly.
I think anyone who is a fan of Boris Karloff, Christopher Lee or horror films in general will delight in seeing "Corridors of Blood".