Bought to replace a Lide 50 for Windows 7, things have moved on quite a notch in the last few years.
The nice and simple set-up takes only a few minutes and the software is so much simpler to use, which is a good thing.
I've stopped using the standard 6x4 settings, as they seem to leave a border on two sides, but if you set it for Auto Detect, then there's no problem. It also scans 4 at a time without chopping the bottom one, which my 50 did.
I haven't found a preview button, which would allow the scan area to be cropped, which I always find useful, but it's not the end of the world.
Speed is definitely improved, although this is a level above the old 50 anyway in terms of performance.
I haven't bothered with any manipulation software (I'm not even sure if any was included), as I always use Photo Elements for a half decent job and only want the scanner to scan old prints, which it does perfectly well.
Update 02/02/11 - You can indeed do previews and presumably adjust crops, but I find that the multi-scan is so simple and useful that I don't bother with anything else. The only time I might use the manual preview is when scanning a cropped area at maximum resolution, which would be useful for increasing picture size.