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Biodegradable in Situ Microparticles for Sustained Protein Delivery

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Biodegradable in Situ Microparticles for Sustained Protein Delivery (Paperback)

by Martin Korber (Author)

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Product details

Paperback: 334 pages
Publisher: VDM Verlag Dr. Muller Aktiengesellschaft & Co. KG (22 Aug 2008)
Language English
ISBN-10: 3639076591
ISBN-13: 978-3639076592
Product Dimensions: 22.8 x 14.8 x 2.2 cm
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Amazon.co.uk Sales Rank: 2,387,765 in Books (See Bestsellers in Books)

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Product Description

Synopsis
The objective of this work was to evaluate the suitability of in situ forming biodegradable microparticles for the controlled delivery of proteins. Particular goals were: a) to evaluate the flexibility of the release patterns of in situ implant and in situ microparticle formulations using hen egg white lysozyme as model protein; b) to characterize, if and how the integrity of the model protein is affected by formulation ingredients, the manufacturing process, sto--rage of the ISM and the release from the formulations; c) to optimize protein delivery from in situ forming implant and microparticle systems, with regard to shape and completeness of the release; d) to find / validate reliable methods allowing to extract and thus to characterize the model protein in biodegradable in situ formulations.

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