I've been using this monitor for 11 days. it has been used exclusively with my PS3 via a HDMI connection. I have no previous experience with High Definition. I like this monitor a lot.
Cables supplied: VGA/VGA, 3.5mm/3.5mm audio, USBB/USBA, UK power, EU power.
As reviewer James Stevens pointed out, HDMI auto switching is disabled by default so you have to press enter a few times until you're on the right input. All of the buttons are located on the right hand side and they are unintuitive, expect to fumble through the menus to get what you want.
This monitor is positively bursting with ports. It has 3.5mm audio in/out sockets at the back, as well as a 3.5mm headphone socket (audio out) on the side for easier access. Just as well really, because the internal speakers are awful. If you plan on anything beyond basic PC usage I wouldn't rely on the E2220HD for your sound. The monitor comes with a neat headphone hook that clips into the vents on the back, a nice touch. I tried to run USB powered speakers through the line out & USB ports, couldn't get it working - until I realised I had to plug the USB input into my ps3 (or pc) to power the USB outputs.
(also, on the subject of ports the product description mentions the VGA port supports the Wii - this is flat out wrong. The Wii wasn't designed to work with PC monitors and attempts to do so cannot guarantee results).
The stand is fairly lightweight, you'll need two hands to do tilt adjustments.
The most important thing, of course, is the picture. Vibrant, crisp, detailed, just great. I will say that on a monitor this size, the difference between 720p and 1080p is virtually zero, both look amazing. The monitor has 5 presets for display: Standard, Movie, Game, Photo, sRGB. This is nice and straightforward. I have seen no lag / input delay at all while gaming.
The price has gone up since I bought it, but it's still a great deal and an easy 5 stars :)