Oliver Sacks, a singularly humane writer and physician, provides the case histories of 20 institutionalised people who are suffering the appalling sickness disease that struck around the time of the first world war (though not connected), whom he encountered professionally in about 1970. Specifically he describes the "Awakening" affect of L-Dopa on these people.
But beware that these histories do not make for comfortable reading as these people suffer in a way that few others have.
As ever, Sacks is absolutely brilliant at seeing the person behind the affliction, and the big message behind the whole book is to argue that medicine is not just an objective scientific activity, but that seeing the subjective "I" of each individual patient in terms of physiology, psychology, social environment etc. is also of vital importance. He supports this position with many examples of how the patients react to changes to their personal cicumstances.
I found the case studies at times harrowing, and was very grateful for the 1982 epilogue contained in my 1990 copy that contained positive updates on a number of the patients.
As well as his own words, Sacks includes quotes from a number of poets (Donne in particular) and philosophers (Kant, Leibnitz, Nitsche) that are used to illustrate his position very effectively.
I am left somewhat in awe of this book and recommend it to anyone with an interest in either medicine or how people come to terms with unbelievably trying circumstances.