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Autism's False Prophets: Bad Science, Risky Medicine, and the Search for a Cure [Hardcover]

Paul A Offit
3.2 out of 5 stars  See all reviews (13 customer reviews)
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Book Description

3 Oct 2008 0231146361 978-0231146364 1
A London researcher was the first to assert that the combination measles-mumps-rubella vaccine known as MMR caused autism in children. Following this "discovery," a handful of parents declared that a mercury-containing preservative in several vaccines was responsible for the disease. If mercury caused autism, they reasoned, eliminating it from a child's system should treat the disorder. Consequently, a number of untested alternative therapies arose, and, most tragically, in one such treatment, a doctor injected a five-year-old autistic boy with a chemical in an effort to cleanse him of mercury, which stopped his heart instead. Children with autism have been placed on stringent diets, subjected to high-temperature saunas, bathed in magnetic clay, asked to swallow digestive enzymes and activated charcoal, and injected with various combinations of vitamins, minerals, and acids. Instead of helping, these therapies can hurt those who are most vulnerable, and particularly in the case of autism, they undermine childhood vaccination programs that have saved millions of lives. An overwhelming body of scientific evidence clearly shows that childhood vaccines are safe and does not cause autism. Yet widespread fear of vaccines on the part of parents persists. In this book, Paul A. Offit, a national expert on vaccines, challenges the modern-day false prophets who have so egregiously misled the public and exposes the opportunism of the lawyers, journalists, celebrities, and politicians who support them. Offit recounts the history of autism research and the exploitation of this tragic condition by advocates and zealots. He considers the manipulation of science in the popular media and the courtroom, and he explores why society is susceptible to the bad science and risky therapies put forward by many antivaccination activists.

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Product details

  • Hardcover: 352 pages
  • Publisher: Columbia University Press; 1 edition (3 Oct 2008)
  • Language: English
  • ISBN-10: 0231146361
  • ISBN-13: 978-0231146364
  • Product Dimensions: 15.2 x 2.8 x 22.9 cm
  • Average Customer Review: 3.2 out of 5 stars  See all reviews (13 customer reviews)
  • Amazon Bestsellers Rank: 794,174 in Books (See Top 100 in Books)
  • See Complete Table of Contents

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Review

Every child has a right to be vaccinated against deadly diseases. We started Every Child By Two to protect children from diseases. It didn't occur to me that I would also have to protect them from misinformation about life-saving vaccines. Paul A. Offit's book sets the facts straight. -- Rosalynn Carter, former first lady, cofounder of Every Child By Two Autism's False Prophets is a compelling story of heartbroken parents, understandably desperate for an explanation of autism, being taken in by false hopes unsupported by genuine science. This book goes to the heart of a question that affects every aspect of American culture and political life. Are public policies to be determined by evidence and reason or by emotions that, however intense they may be, have nothing to do with reality? -- Susan Jacoby, author of The Age of American Unreason A definitive analysis of a dangerous and unnecessary controversy that has put the lives of children at risk. Paul A. Offit shows how bad science can take hold of the public consciousness and lead to personal decisions that endanger the health of small children. Every parent who has doubts about the wisdom of vaccinating their kids should read this book. -- Peter C. Doherty, Ph.D., St. Jude's Children's Research Hospital and Nobel Laureate in Medicine for fundamental contributions in Immunology In his latest book Paul A. Offit unfolds the story of autism, infectious diseases, and immunization that has captivated our attention for the last decade. His lively account explores the intersection of science, special interests, and personal courage. It is provocative reading for anyone whose life has been touched by the challenge of autism spectrum disorders. -- Susan K. Klein, MD, Ph.D., Case Western Reserve Hospital, and Rainbow Babies and Children's Hospital, Case Medical Center [A] thoughtful and readable study. Library Journal (starred review) 8/1/08 Enlightening, highly readable and... timely. -- Rahul K. Parikh, M.D. Salon.com 9/22/08 Arguably the most courageous and most knowledgeable scientist about vaccines in the United States. -- Robert Goldberg New York Post 9/14/08 [Dr. Offit] has done a huge public service by exposing the tragic and dangerous place the anti-vaccine hysteria has taken us. -- Huntly Collins Philadelphia Inquirer 9/21/08 An invaluable chronicle that relates some of the many ways in which the vulnerabilities of anxious parents have been exploited. -- Linda Seebach Wall Street Journal 9/23/08 A good read and an important piece of work. -- Lisa Jo Rudy About.com 9/16/08 More than a book about a disease, it is an ode to uncorrupted science and a cautionary tale that data alone is never enough. SEED magazine Sept / Oct [Offit] provides important insight into the fatal flaws of the key arguments of vaccine alarmists. Buffalo News 10-12-08 A very good read. -- Dom Giordano The Bulletin 10/3/08 A sobering indictment. -- Isabelle Rapin, M.D. Neurology Today 1/15/09 Highly recommended. Choice 3/1/09 A fascinating read... Eloquently and clearly written. -- Stan L. Block, MD Infectious Diseases in Children 2/1/2009 A very helpful book for both medical personnel and parents. The New England Journal of Medicine 3/12/09 The book is a fantastic read. I recommend it to all physicians and their patients and families. -- Brian Alverson, MD Archives of Pediatric & Adolescent Medicine 4/1/09 This is a powerful book which should be read by all professionals working in the area ofmedicine. -- Michael Fitzgerald Social History of Medicine Vol 22, No 1 Paul A. Offit is one of the most respected scientists and clinicians in a field of vital importance to public health. -- Patricia M. Rodier BioScience 5/1/09 [This] book doesn't just show that the anti-vaccine activists are wrong; it attempts to explain why, in our culture, they tend to win. -- Jason Fagone Philadelphia Magazine 6/1/09 Detailed but easily readable... should be required reading for any parents who are considering denying vaccination to their children. Communication: The Magazine of the National Autistic Society Summer 09 Arguably the most detailed and thorough history available of the current anti-vaccine movement. -- Roy Richard Grinker Journal of Autism and Developmental Disorders Vol 39, No 3 [A] must-read... it will keep pediatricians and pediatric neurologists awake over the nightmarish possibilities of pseudoscience in the 21st century. -- Roger A. Brumback, M.D. Journal of Child Neurology Vol. 24, No. 2 The vast range of professionals who may be enriched, professionally, by the book's contents extends to: psychologists, psychiatrists, neurologists, neuroscientists, speech pathologists, pediatricians, primary care physicians, geneticists, virologists, immunologists, vaccine experts, nurses, infectious disease experts, internists, gastroenterologists, epidemiologists, public health professionals, special education teachers, bioethicists, biochemists, biologists, biostatisticians, endocrinologists, pharmacists, pharmacologists, pharmaceutical industry professionals, health policy makers, journalists, politicians, and trial lawyers. -- Leo Uzych Metapsychology 3/20/11 Seeking to help readers realize the truth about Autism, Autism's False Prophets is a much need read, not to be missed. Midwest Book Review August 2010

About the Author

Paul A. Offit, MD, FAAP is the chief of Infectious Diseases and the director of the Vaccine Education Center at the Children's Hospital of Philadelphia as well as the Maurice R. Hilleman Professor of Vaccinology and professor of pediatrics at the University of Pennsylvania School of Medicine. He has received numerous awards, including the J. Edmund Bradley Prize for Excellence in Pediatrics from the University of Maryland School of Medicine, the Young Investigator Award in Vaccine Development from the Infectious Diseases Society of America, and a Research Career Development Award from the National Institutes of Health. An international expert on rotavirus-specific immune responses, Dr. Offit is the coinventor of the rotavirus vaccine RotaTeq, for which he received the Jonas Salk Award from the Association for Professionals in Infection Control and Epidemiology, the Gold Medal from the Children's Hospital of Philadelphia, and the Stanley A. Plotkin Award in Vaccinology from the Pediatric Infectious Diseases Society. He has donated all royalties from sales of this book to autism research.

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Customer Reviews

Most Helpful Customer Reviews
3 of 3 people found the following review helpful
4.0 out of 5 stars Timely, Necessary, and Informative 31 Oct 2010
By SimonT
Format:Hardcover
This is a very well-written and researched book that highlights much of the bad science and downright quackery that afflicts autism research. Of course it will get the negative reviews from Wakefield acolytes who will not want parents of autistic children, of whom I am one, to read it. The main problem for this book though is that many who hold to the vaccines/thimersal autism link will never be convinced by any amount of rigorous science, some of these genuinely believe in these unfounded theories but there are many who have a vested and financial interest in promoting unfounded and discredited hypotheses. This book represents an important antidote to all this and the author is to be commended for his bravery and honesty in writing it. My only quibble with it, hence four instead of five stars, is the author's over-confidence in the probity of the pharmaceutical industry generally. Recent cases, most recently the huge fine imposed on GSK for poor manufacturing practices at it's Puerto Rico plant shake public confidence in this industry. As the old saying goes: "Follow the money". The whole area of autism is sadly afflicted with quackery and chicanery and with parents desperate to believe in anything, it is likely to remain so until the true causes, genetic and/or environmental, are known. In the meantime, parents need to be able to distinguish good science from bad and this book is certainly instructive in this regard.
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32 of 38 people found the following review helpful
By AB
Format:Hardcover
Paul Offit's book is a must-read for parents of a child with a recent autism diagnosis. As a parent of an autistic child myself, I can fully understand the heart-wrenching desire to find a CURE or understand WHY it happened. I'm ordinarily very sceptical of alternative medicine, but at times I have gone through periods of wanting to do anything, try anything, pay for anything that will improve our child's condition - it's a completely natural reaction - I'm a parent. Fortunately before doing so I took the time to look at the scientific backup for the various interventions (Research Autism being a good resource) and discovered that there is very little and often no scientific support for most of the interventions claimed. The interventions which appear to have the most positive effect (e.g. ABA) are actually hard work. It seems there is no miracle cure that your wallet alone will cure - if there was, I would be using it and it would probably be available on the NHS. This is a very difficult fact for people to accept in this modern world where there is an immediate medical fix for most things. As someone else once commented, if someone is promising to you that they have the cure for autism and/or understand definitively what "causes" it (or its symptoms), ask them whether they have the Nobel Prize. Because the person who actually discovers these things would surely win it. Otherwise it's just somebody's hunch. The book warns to be aware of the parental placebo and parent testimonials. If you invest a lot of money in a particular remedy, you would (consciously or unconsciously) rather see an improvement than admit you have wasted your time and money. And don't underestimate how much children develop without intervention. The people who espouse alternative theories are very happy to dismiss "science" as an inexact procedure without all the answers but would baulk at the idea of flying in a plane that hadn't been rigorously tested by engineers. So why are people happy to accept a lesser standard of evidence when experimenting on their children? What this book also does is set out exactly why parents should be wary of people willing to tell them that they have the answers (at a price), and explains some of the conflicts of interest these people have. This book encourages you to think critically - don't be taken in for "cargo cult" science - there are plenty of people willing to give advice which is dressed up in the language of science and medicine with big words which superficially appears impressive, but actually has no substance. My advice to parents - having read the book, work out how money you would be prepared to spend to find a cure for your child and then spend it on your family for things with proven benefit for everybody (holidays, child care/respite, family activities, etc). I read another quote somewhere recently about a study which showed that families who accepted their children's disability often enjoyed a new cohesiveness; while those who experienced guilt (because they thought they caused it or weren't doing enough to cure it) are more likely to have problems. There are also some good reviews of this book at amazon.com, and google search "great autism rip-off" for a (surprisingly) good article in the Daily Mail.
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35 of 42 people found the following review helpful
5.0 out of 5 stars Unputdownable 20 Oct 2008
By Dyson
Format:Hardcover
I read this book in a single session - it rattles along with great narrative pace, and it was impossible not to want to read the next chapter just "to see what happened next". Despite the clearly expert scientific status of the author, there is no turgid scientific jargon to impede the flow, but it is meticulously referenced so anyone can check the medical evidence for themselves if they so wish.

Offit eloquently takes us on a rollercoaster ride looking at the putative causes and cures of autism over the recent past, with the neat technique of seemingly building a case in support of those who would blame vaccines for causing autism, before comprehensively demolishing this in the following chapter. He ends with an assessment of the media's role in the vaccine-autism scare, and an insightful commentary on society's attitude and grasp of science.

Overall, there was little to fault, though there could have been more made of culpability of the media regarding the MMR Wakefield saga in the UK, and the unhelpful (and frankly negative) contributions made by those in UK Government and the higher echelons of medical politics. (Tony Blair's refusal to say that his own son had recieved MMR merely caused further panic among parents - something he and his advisers should have known).

I have read the contributions of the book's negative reviewers. It is clear they are dyed-in-the-wool antivaccinationists who have not even bothered to read this book, and just want to snipe at the author. Shame on them. Their status as reviewers is hardly enhanced by their mean-spiritedness.
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Most Recent Customer Reviews
5.0 out of 5 stars Evidence-based medicine is better than faith-based!
This splendid book exposes the dangers of backing faith-based medicine over evidence-based medicine. Read more
Published 5 months ago by William Podmore
1.0 out of 5 stars Propaganda pure and simple
I'm afraid this book in no way sets the record straight. It is based on carefully selected research that aims to prove that thimerosal and the measles vaccine are not the cause of... Read more
Published 14 months ago by Mr. J. S. Stallick
3.0 out of 5 stars conflict of interest
read this book and judge for yourself but remember that Paul Offit is the co-inventor of the RotaTeq vaccine against rotavirus produced by Merck.
Published on 24 May 2010 by sendmenoflowers
5.0 out of 5 stars Excellent
I am a mum of two severely autistic children and have just finished this excellent and compelling book. Read more
Published on 2 Jan 2009 by Anne
5.0 out of 5 stars Excellent and accurate account of false promises
I had been waiting for this book for a while (indeed, due to the long delivery times, I waited longer than anticipated). Read more
Published on 18 Nov 2008 by Dr. C. Becker
1.0 out of 5 stars Just not true
Who is paying this person? And why write a whole book about one theory? Children have improved dramatically (some lose diagnosis!) following medical treatment. Read more
Published on 28 Sep 2008 by Marvo
1.0 out of 5 stars An exercise in self justification and proffiteering
The fundamental point about this book is not that the author knows anything about autism, but that he is Merck's leading vaccine scientist, and he is desperately trying to shift... Read more
Published on 20 Sep 2008 by John Stone
1.0 out of 5 stars Paul's Profit is not False
How anybody can take a book seriously written by a person who has ammased huge wealth from selling a vaccine is beyond me. Read more
Published on 20 Sep 2008 by mark A
1.0 out of 5 stars Not helpfull at all
If you want to help your child with autism do not pay for or read this book, full of doom and gloom and historical references that are outdated and no mention of how to help and... Read more
Published on 20 Sep 2008 by louise
5.0 out of 5 stars Fascinating for parents of autistic children
I read a a review copy of the book and I found it a real page turner. Dr Offit tells the reader the inside story of how the MMR and mercury containing vaccines came to be... Read more
Published on 4 Sep 2008 by K. Leitch
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