This is Book 2 of the Annihilation Wave story arc where Annihilus attempts to take over the universe. Don't be put off by Annihilus' presence! I'm sure you have seen Annihilus getting whipped by the Fantastic Four time and time again, this time, however he is playing for keeps.
The first book opens contains This title collects collecting "Annihilation: Silver Surfer" numbered 1-4, "Annihilation: Super-Skrull" numbered 1-4 and "Annihilation: Ronan" numbered 1-4. The Silver Surfer story is pure heaven. I was slightly disappointed by the Super Skrull chapter, but that doesn't detract too much from this essential piece of reading.
This, Annihilation Wave story, is best thing I've read from Marvel in decades and nods its head to the other great story, the Infinity Gaunlet arc by Jim Starlin in the early 1990s.
While the new "Utimate" branded titles are a decent re-telling of some classic stories, this is much more and shakes the Marvel Universe to its foundations (unlike the rather tame Civil War saga). Starring the most powerful characters in Marvel. Annihilus, Drax, Ronan, The Silver Surfer (+ all the other heralds) Galactus, Thanos, Nova, and many many more.
Best of all there is no Fantastic Four, no x-Men, and no Avengers. It's almost pure Sci-Fi told within the Marvel Universe framework.
Get Book 1 Annihilation Book 1 TPB: Bk. 1 (Annihilation)
and Book 3 Annihilation Book 3 TPB: Bk. 3 (Annihilation)
and settle down for an awesome experience.