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Biomedical Surfaces (Engineering in Medicine & Biology) Hardcover – 29 Feb 2008


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Jeremy Ramsden was educated at the Universities of Cambridge and Princeton and the Ecole Polytechnique Fédérale de Lausanne, where he obtained his doctorate in the Institute of Chemical Physics for research on semiconductor nanoparticles. Visiting scientist at the Eidgenössische Technische Hochschule (Laboratory of Chemical Engineering), Zürich (1993) and the Biocenter (Institute of Biophysics) of the Hungarian Academy of Sciences in Szeged (1987). Privat-Docent for Biophysical Chemistry, Faculty of Natural Philosophy, University of Basel (Switzerland) 1994-2012. Professor and Chair of Nanotechnology at Cranfield University (formerly Cranfield Institute of Technology) (UK) 2002-2011. Research Director for Bionanotechnology, Cranfield University at Kitakyushu (Japan) 2003-2009. His main research focus nowadays is complex adaptive systems and emergent nano-info-bio-cogno converging technologies. He has authored or coauthored more than 200 research articles published in international refereed journals, made a comparable number of conference presentations, co-invented three patents, chaired several international conferences, workshops etc. on molecular recognition, complexity and germane topics, and served as visiting professor in Argentina, France, Hungary and Japan. He is a Fellow of the Institute of Materials, Minerals and Mining (London) and a IUPAC Fellow.

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Introduction--Definition of Biomaterials. The Role of Surfaces in Governing Biomaterial Performance. Modifications to Surfaces in Contact with Biological Media (Biofluids, Tissues, Cells).

The Adsorption of Biomacromolecules--Physical--Chemical Fundamentals.

Haemocompatibility--Processes in Which Biomaterials Are in Contact with Biofluids. Stents. Heart Valves. Dialysis Machines. Design Issues Involving Suppression of Biomacromolecule Absorption or Selective Adsorption.

Lubrication--Materials Acting as Lubricants Between Solid Surfaces. Tribology of the Surfaces. Wear Issues. Particle Release from Prostheses. Mechanical Fatigue.

Cells and Tissues--Biocompatibility with Hard and Soft Tissues. Protein Adsorption and Desorption. Information Flow Between Surface and Cell. Immune Cell Response and Behavior. Assimilation Issues. Infection Risks.

Drug Delivery Surfaces--General Properties of Nano- and Microporous Drug Delivery Materials. Percolation Theory. Interactions of Drug Delivery Particles and Biological Media.

Prospects for Smart and Nano Materials--Smart Surfaces. Interactions Between Cells/Tissues and Adaptive Nano Materials.

About the Author

Jeremy Ramsden is a professor of nanotechnology in the Materials Department of Cranfield University, United Kingdom. He has published over 100 research articles covering topics in adsorption and desorption, biological macromolecules, and self-assembly and organizing processes at the nanoscale, and has chaired several international conferences devoted to biomolecular interactions. He is editor-in-chief of the Journal of Biological Physics and Chemistry, and founder of the MEMOCS research consortium uniting a dozen academic research groups and industrial firms in developing integrated-optical membrane-based sensors for medical and environmental applications. Dr. Ramsden studied Natural Sciences at Cambridge University and received his Ph.D. from the Institute of Chemical Physics, Swiss Federal Institute of Technology in Lausanne.

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